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KDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells
Triple-negative breast cancer (TNBC) is very aggressive and lacks specific therapeutic targets. Ribosome RNAs (rRNAs) are central components of ribosomes and transcribed in nucleoli, and the level of rRNA transcription greatly affects ribosome production and cell proliferation. We have reported that...
Autores principales: | Okamoto, Kengo, Tanaka, Yuji, Ogasawara, Sachiko, Obuse, Chikashi, Nakayama, Jun-ichi, Yano, Hirohisa, Tsuneoka, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677663/ https://www.ncbi.nlm.nih.gov/pubmed/31413816 http://dx.doi.org/10.18632/oncotarget.27092 |
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