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Circulating CXCR5(−)PD-1(hi) peripheral T helper cells are associated with progression to type 1 diabetes
AIMS/HYPOTHESIS: Type 1 diabetes is preceded by a period of asymptomatic autoimmunity characterised by positivity for islet autoantibodies. Therefore, T helper cell responses that induce B cell activation are likely to play a critical role in the disease process. Here, we aimed to evaluate the role...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677711/ https://www.ncbi.nlm.nih.gov/pubmed/31270583 http://dx.doi.org/10.1007/s00125-019-4936-8 |