Sharing of heteroplasmies between human liver lobes varies across the mtDNA genome

Mitochondrial DNA (mtDNA) heteroplasmy (intra-individual variation) varies among different human tissues and increases with age, suggesting that the majority of mtDNA heteroplasmies are acquired, rather than inherited. However, the extent to which heteroplasmic sites are shared across a tissue remai...

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Detalles Bibliográficos
Autores principales: Hübner, Alexander, Wachsmuth, Manja, Schröder, Roland, Li, Mingkun, Eis-Hübinger, Anna Maria, Madea, Burkhard, Stoneking, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677727/
https://www.ncbi.nlm.nih.gov/pubmed/31375696
http://dx.doi.org/10.1038/s41598-019-47570-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677727/
https://www.ncbi.nlm.nih.gov/pubmed/31375696
http://dx.doi.org/10.1038/s41598-019-47570-1

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