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Sharing of heteroplasmies between human liver lobes varies across the mtDNA genome
Mitochondrial DNA (mtDNA) heteroplasmy (intra-individual variation) varies among different human tissues and increases with age, suggesting that the majority of mtDNA heteroplasmies are acquired, rather than inherited. However, the extent to which heteroplasmic sites are shared across a tissue remai...
Autores principales: | Hübner, Alexander, Wachsmuth, Manja, Schröder, Roland, Li, Mingkun, Eis-Hübinger, Anna Maria, Madea, Burkhard, Stoneking, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677727/ https://www.ncbi.nlm.nih.gov/pubmed/31375696 http://dx.doi.org/10.1038/s41598-019-47570-1 |
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