In silico design and optimization of selective membranolytic anticancer peptides

Membranolytic anticancer peptides represent a potential strategy in the fight against cancer. However, our understanding of the underlying structure-activity relationships and the mechanisms driving their cell selectivity is still limited. We developed a computational approach as a step towards the...

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Detalles Bibliográficos
Autores principales: Gabernet, Gisela, Gautschi, Damian, Müller, Alex T., Neuhaus, Claudia S., Armbrecht, Lucas, Dittrich, Petra S., Hiss, Jan A., Schneider, Gisbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677754/
https://www.ncbi.nlm.nih.gov/pubmed/31375699
http://dx.doi.org/10.1038/s41598-019-47568-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677754/
https://www.ncbi.nlm.nih.gov/pubmed/31375699
http://dx.doi.org/10.1038/s41598-019-47568-9

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