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Class IIa HDACs regulate learning and memory through dynamic experience-dependent repression of transcription

The formation of new memories requires transcription. However, the mechanisms that limit signaling of relevant gene programs in space and time for precision of information coding remain poorly understood. We found that, during learning, the cellular patterns of expression of early response genes (ER...

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Detalles Bibliográficos
Autores principales: Zhu, Yongchuan, Huang, Min, Bushong, Eric, Phan, Sebastien, Uytiepo, Marco, Beutter, Elizabeth, Boemer, Daniel, Tsui, Kristin, Ellisman, Mark, Maximov, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677776/
https://www.ncbi.nlm.nih.gov/pubmed/31375688
http://dx.doi.org/10.1038/s41467-019-11409-0