Cargando…

TonEBP Regulates PCNA Polyubiquitination in Response to DNA Damage through Interaction with SHPRH and USP1

Polyubiquitination of proliferating cell nuclear antigen (PCNA) regulates the error-free template-switching mechanism for the bypass of DNA lesions during DNA replication. PCNA polyubiquitination is critical for the maintenance of genomic integrity; however, the underlying mechanism is poorly unders...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kang, Hyun Je, Park, Hyun, Yoo, Eun Jin, Lee, Jun Ho, Choi, Soo Youn, Lee-Kwon, Whaseon, Lee, Kyoo-young, Hur, Jin-Hoe, Seo, Jeong Kon, Ra, Jae Sun, Lee, Eun-A., Myung, Kyungjae, Kwon, Hyug Moo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677787/ https://www.ncbi.nlm.nih.gov/pubmed/31376680 http://dx.doi.org/10.1016/j.isci.2019.07.021

Ejemplares similares

TonEBP suppresses IL-10-mediated immunomodulation
por: Choi, Soo Youn, et al.
Publicado: (2016)

Modulation of TonEBP activity by SUMO modification in response to hypertonicity
por: Kim, Jeong-Ah, et al.
Publicado: (2014)

TonEBP Promotes β-Cell Survival under ER Stress by Enhancing Autophagy
por: Kang, Hyun Je, et al.
Publicado: (2020)

TonEBP recognizes R-loops and initiates m6A RNA methylation for R-loop resolution
por: Kang, Hyun Je, et al.
Publicado: (2020)

Transcriptional Regulator TonEBP Mediates Oxidative Damages in Ischemic Kidney Injury
por: Yoo, Eun Jin, et al.
Publicado: (2019)

TonEBP suppresses adipogenesis and insulin sensitivity by blocking epigenetic transition of PPARγ2
por: Ho Lee, Jun, et al.
Publicado: (2015)

TonEBP Suppresses the HO-1 Gene by Blocking Recruitment of Nrf2 to Its Promoter
por: Yoo, Eun Jin, et al.
Publicado: (2019)

TonEBP in dendritic cells mediates pro-inflammatory maturation and Th1/Th17 responses
por: Ye, Byeong Jin, et al.
Publicado: (2020)

TonEBP and SMIT expression in human placenta
por: Shin, Jung-A, et al.
Publicado: (2012)

Microglial TonEBP mediates LPS-induced inflammation and memory loss as transcriptional cofactor for NF-κB and AP-1
por: Jeong, Gyu Won, et al.
Publicado: (2020)

TonEBP/NFAT5 promotes obesity and insulin resistance by epigenetic suppression of white adipose tissue beiging
por: Lee, Hwan Hee, et al.
Publicado: (2019)

TonEBP in Myeloid Cells Promotes Obesity-Induced Insulin Resistance and Inflammation Through Adipose Tissue Remodeling
por: Lee, Hwan Hee, et al.
Publicado: (2022)

LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding
por: Lee, Hwan Hee, et al.
Publicado: (2016)

Transcription Factor TonEBP Stimulates Hyperosmolality-Dependent Arginine Vasopressin Gene Expression in the Mouse Hypothalamus
por: Kim, Dong Hee, et al.
Publicado: (2021)

TonEBP/NFAT5 haploinsufficiency attenuates hippocampal inflammation in high-fat diet/streptozotocin-induced diabetic mice
por: Lee, Jong Youl, et al.
Publicado: (2017)

TonEBP Haploinsufficiency Attenuates Microglial Activation and Memory Deficits in Middle-Aged and Amyloid β Oligomer-Treated Mice
por: Lee, Jong Youl, et al.
Publicado: (2023)

TonEBP suppresses adipocyte differentiation via modulation of early signaling in 3T3-L1 cells
por: Kim, Soo Jin, et al.
Publicado: (2016)

The TLR-2/TonEBP signaling pathway regulates 29-kDa fibronectin fragment-dependent expression of matrix metalloproteinases
por: Hwang, Hyun Sook, et al.
Publicado: (2021)

TonEBP modulates the protective effect of taurine in ischemia-induced cytotoxicity in cardiomyocytes
por: Yang, Y J, et al.
Publicado: (2015)

TonEBP regulates the hyperosmotic expression of aquaporin 1 and 5 in the intervertebral disc
por: Snuggs, J. W., et al.
Publicado: (2021)

Osmoprotective Transcription Factor NFAT5/TonEBP Modulates Nuclear Factor-κB Activity
por: Roth, Isabelle, et al.
Publicado: (2010)

Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus
por: Liu, Chao, et al.
Publicado: (2017)

Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination
por: Motegi, Akira, et al.
Publicado: (2006)

Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: Evolving role of TonEBP
por: Johnson, Zariel I., et al.
Publicado: (2014)

Involvement of TonEBP/NFAT5 in osmoadaptative response of human retinal pigmented epithelial cells to hyperosmolar stress
por: Libert, Sarah, et al.
Publicado: (2016)

TonEBP/NFAT5 regulates ACTBL2 expression in biomechanically activated vascular smooth muscle cells
por: Hödebeck, Maren, et al.
Publicado: (2014)

Focal adhesion kinase regulates the activity of the osmosensitive transcription factor TonEBP/NFAT5 under hypertonic conditions
por: Neuhofer, Wolfgang, et al.
Publicado: (2014)

Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation
por: Choi, Hyowon, et al.
Publicado: (2019)

Genistein‐Calcitriol Mitigates Hyperosmotic Stress‐Induced TonEBP, CFTR Dysfunction, VDR Degradation and Inflammation in Dry Eye Disease
por: Panigrahi, Trailokyanath, et al.
Publicado: (2020)

Osmolyte regulation by TonEBP/NFAT5 during anoxia-recovery and dehydration–rehydration stresses in the freeze-tolerant wood frog (Rana sylvatica)
por: Al-attar, Rasha, et al.
Publicado: (2017)

Mediator of DNA Damage Checkpoint 1 (MDC1) Contributes to High NaCl-Induced Activation of the Osmoprotective Transcription Factor TonEBP/OREBP
por: Kunin, Margarita, et al.
Publicado: (2010)

Regulation of PCNA polyubiquitination in human cells
por: Brun, Jan, et al.
Publicado: (2010)

NFAT5/TonEBP Limits Pulmonary Vascular Resistance in the Hypoxic Lung by Controlling Mitochondrial Reactive Oxygen Species Generation in Arterial Smooth Muscle Cells
por: Laban, Hebatullah, et al.
Publicado: (2021)

Preferential digestion of PCNA-ubiquitin and p53-ubiquitin linkages by USP7 to remove polyubiquitin chains from substrates
por: Masuda, Yuji, et al.
Publicado: (2019)

High NaCl–induced activation of CDK5 increases phosphorylation of the osmoprotective transcription factor TonEBP/OREBP at threonine 135, which contributes to its rapid nuclear localization
por: Gallazzini, Morgan, et al.
Publicado: (2011)

ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin
por: Lee, Kyoo-young, et al.
Publicado: (2013)

The Emerging Role of Circ-SHPRH in Cancer
por: Ju, Xinyue, et al.
Publicado: (2021)

Regulation of HLTF-mediated PCNA polyubiquitination by RFC and PCNA monoubiquitination levels determines choice of damage tolerance pathway
por: Masuda, Yuji, et al.
Publicado: (2018)

BMP-2 and TGF-β Stimulate Expression of β1,3-Glucuronosyl Transferase 1 (GlcAT-1) in Nucleus Pulposus Cells Through AP1, TonEBP, and Sp1: Role of MAPKs
por: Hiyama, Akihiko, et al.
Publicado: (2010)

Short-range end resection requires ATAD5-mediated PCNA unloading for faithful homologous recombination
por: Park, Su Hyung, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sfd7hjf711tslp4225v9tu20eu