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Phc2 controls hematopoietic stem and progenitor cell mobilization from bone marrow by repressing Vcam1 expression

The timely mobilization of hematopoietic stem and progenitor cells (HSPCs) is essential for maintaining hematopoietic and tissue leukocyte homeostasis. Understanding how HSPCs migrate between bone marrow (BM) and peripheral tissues is of great significance in the clinical setting, where therapeutic...

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Detalles Bibliográficos
Autores principales: Bae, Joonbeom, Choi, Sang-Pil, Isono, Kyoichi, Lee, Ji Yoon, Park, Si-Won, Choi, Chang-Yong, Han, Jihye, Kim, Sang-Hoon, Lee, Han-Hyoung, Park, Kyungmin, Jin, Hyun Yong, Lee, Suk Jun, Park, Chung-Gyu, Koseki, Haruhiko, Lee, Young Sik, Chun, Taehoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677815/
https://www.ncbi.nlm.nih.gov/pubmed/31375680
http://dx.doi.org/10.1038/s41467-019-11386-4