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A Novel Cell-Penetrating Antibody Fragment Inhibits the DNA Repair Protein RAD51
DNA damaging chemotherapies are successful in cancer therapy, however, the damage can be reversed by DNA repair mechanisms that may be up-regulated in cancer cells. We hypothesized that inhibiting RAD51, a protein involved in homologous recombination DNA repair, would block DNA repair and restore th...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677837/ https://www.ncbi.nlm.nih.gov/pubmed/31375703 http://dx.doi.org/10.1038/s41598-019-47600-y |