A portable epigenetic switch for bistable gene expression in bacteria

We describe a portable epigenetic switch based on opvAB, a Salmonella enterica operon that undergoes bistable expression under DNA methylation control. A DNA fragment containing the opvAB promoter and the opvAB upstream regulatory region confers bistability to heterologous genes, yielding OFF and ON...

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Detalles Bibliográficos
Autores principales: Olivenza, David R., Nicoloff, Hervé, Sánchez-Romero, María Antonia, Cota, Ignacio, Andersson, Dan I., Casadesús, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677893/
https://www.ncbi.nlm.nih.gov/pubmed/31375711
http://dx.doi.org/10.1038/s41598-019-47650-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677893/
https://www.ncbi.nlm.nih.gov/pubmed/31375711
http://dx.doi.org/10.1038/s41598-019-47650-2

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