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Re-positioning of known drugs for Pim-1 kinase target using molecular docking analysis

The Concept of reusing existing drugs for new targets is gaining momentum in recent years because of cost-effectiveness as safety and toxicology data are already available. Therefore, it is of interest to re-profile known drugs against the Pim-1 kinase target using molecular docking analysis. Result...

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Detalles Bibliográficos
Autores principales: Arrouchi, Housna, Lakhlili, Wiame, Ibrahimi, Azeddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677905/
https://www.ncbi.nlm.nih.gov/pubmed/31435157
http://dx.doi.org/10.6026/97320630015116