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Design of novel JAK3 Inhibitors towards Rheumatoid Arthritis using molecular docking analysis

Multiple cytokines play a pivotal role in the pathogenesis of Rheumatoid Arthritis by inducing intracellular signaling and it is known that the members of the Janus kinase (JAK) family are essential for such signal transduction. Janus kinase 3 is a tyrosine kinase that belongs to the Janus family of...

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Detalles Bibliográficos
Autores principales: Jain, Divya, Udhwani, Trishang, Sharma, Shreshtha, Gandhe, Aishwarya, Reddy, Palugulla Bhaskar, Nayarisseri, Anuraj, Singh, Sanjeev Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677909/
https://www.ncbi.nlm.nih.gov/pubmed/31435152
http://dx.doi.org/10.6026/97320630015068