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In vitro and in vivo evaluation of a single chain antibody fragment generated in planta with potent rabies neutralisation activity

Rabies causes more than 60,000 human deaths annually in areas where the virus is endemic. Importantly, rabies is one of the few pathogens for which there is no treatment following the onset of clinical disease with the outcome of infection being death in almost 100% of cases. Whilst vaccination, and...

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Detalles Bibliográficos
Autores principales: Phoolcharoen, Waranyoo, Banyard, Ashley C., Prehaud, Christophe, Selden, David, Wu, Guanghui, Birch, Colin P.D., Szeto, Tim H., Lafon, Monique, Fooks, Anthony R., Ma, Julian K.-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677913/
https://www.ncbi.nlm.nih.gov/pubmed/29523449
http://dx.doi.org/10.1016/j.vaccine.2018.02.057