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Susceptible loci associated with autoimmune disease as potential biomarkers for checkpoint inhibitor-induced immune-related adverse events

Unprecedented successes regarding cancer immunotherapy have been achieved, in which therapeutic agents are used to target immune cells rather than cancer cells. The most effective immunotherapy to date is the group of immune checkpoint inhibitors (CPI), targeting, for example, cytotoxic T-lymphocyte...

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Detalles Bibliográficos
Autores principales: Hoefsmit, Esmée P., Rozeman, Elisa A., Haanen, John B. A. G., Blank, Christian U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677983/
https://www.ncbi.nlm.nih.gov/pubmed/31423333
http://dx.doi.org/10.1136/esmoopen-2018-000472