Intramolecular Domain Movements of Free and Bound pMHC and TCR Proteins: A Molecular Dynamics Simulation Study

The interaction of antigenic peptides (p) and major histocompatibility complexes (pMHC) with T-cell receptors (TCR) is one of the most important steps during the immune response. Here we present a molecular dynamics simulation study of bound and unbound TCR and pMHC proteins of the LC13-HLA-B*44:05-...

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Detalles Bibliográficos
Autores principales: Karch, Rudolf, Stocsits, Claudia, Ilieva, Nevena, Schreiner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678086/
https://www.ncbi.nlm.nih.gov/pubmed/31337065
http://dx.doi.org/10.3390/cells8070720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678086/
https://www.ncbi.nlm.nih.gov/pubmed/31337065
http://dx.doi.org/10.3390/cells8070720

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