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The IL4I1 Enzyme: A New Player in the Immunosuppressive Tumor Microenvironment
The high metabolic needs of T lymphocytes in response to activation make them particularly vulnerable to modifications of their biochemical milieu. Immunosuppressive enzymes produced in the tumor microenvironment modify nutrient availability by catabolizing essential or semi-essential amino acids an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678094/ https://www.ncbi.nlm.nih.gov/pubmed/31330829 http://dx.doi.org/10.3390/cells8070757 |