Cargando…

The IL4I1 Enzyme: A New Player in the Immunosuppressive Tumor Microenvironment

The high metabolic needs of T lymphocytes in response to activation make them particularly vulnerable to modifications of their biochemical milieu. Immunosuppressive enzymes produced in the tumor microenvironment modify nutrient availability by catabolizing essential or semi-essential amino acids an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Molinier-Frenkel, Valérie, Prévost-Blondel, Armelle, Castellano, Flavia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678094/ https://www.ncbi.nlm.nih.gov/pubmed/31330829 http://dx.doi.org/10.3390/cells8070757

Ejemplares similares

What role for AHR activation in IL4I1-mediated immunosuppression ?
por: Castellano, Flavia, et al.
Publicado: (2021)

Editorial: Immunosuppressive Amino Acid Catabolizing Enzymes in Heallth and Disease
por: Castellano, Flavia, et al.
Publicado: (2021)

IL4I1 Accelerates the Expansion of Effector CD8(+) T Cells at the Expense of Memory Precursors by Increasing the Threshold of T-Cell Activation
por: Puiffe, Marie-Line, et al.
Publicado: (2020)

An Overview of l-Amino Acid Oxidase Functions from Bacteria to Mammals: Focus on the Immunoregulatory Phenylalanine Oxidase IL4I1
por: Castellano, Flavia, et al.
Publicado: (2017)

Antibacterial Properties of the Mammalian L-Amino Acid Oxidase IL4I1
por: Puiffe, Marie-Line, et al.
Publicado: (2013)

Control of T-Cell Activation and Signaling by Amino-Acid Catabolizing Enzymes
por: Castellano, Flavia, et al.
Publicado: (2020)

IL4I1 binds to TMPRSS13 and competes with SARS-CoV-2 spike
por: Gatineau, Jérôme, et al.
Publicado: (2022)

Key Players of the Immunosuppressive Tumor Microenvironment and Emerging Therapeutic Strategies
por: Park, Kevin, et al.
Publicado: (2022)

An IL-4/21 Inverted Cytokine Receptor Improving CAR-T Cell Potency in Immunosuppressive Solid-Tumor Microenvironment
por: Wang, Yi, et al.
Publicado: (2019)

Exosome-Mediated Immunosuppression in Tumor Microenvironments
por: Xie, Qi-Hui, et al.
Publicado: (2022)

Harnessing nanomedicine to overcome the immunosuppressive tumor microenvironment
por: Sun, Bo, et al.
Publicado: (2020)

The roles of curcumin in regulating the tumor immunosuppressive microenvironment
por: Wang, Yizhi, et al.
Publicado: (2020)

Immunosuppressive Roles of Galectin-1 in the Tumor Microenvironment
por: Huang, Yanyu, et al.
Publicado: (2021)

Overcoming the Immunosuppressive Tumor Microenvironment in Multiple Myeloma
por: Uckun, Fatih M.
Publicado: (2021)

Old Stars and New Players in the Brain Tumor Microenvironment
por: Parmigiani, Elena, et al.
Publicado: (2021)

CTLA4-Mediated Immunosuppression in Glioblastoma is Associated with the Infiltration of Macrophages in the Tumor Microenvironment
por: Guan, Xiudong, et al.
Publicado: (2021)

Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment
por: Chanmee, Theerawut, et al.
Publicado: (2014)

Tumor-associated macrophages: an effective player of the tumor microenvironment
por: Basak, Udit, et al.
Publicado: (2023)

New strategies for melanoma immunotherapy: How to overcome immunosuppression in the tumor microenvironment
por: Umansky, Viktor
Publicado: (2012)

CD200 promotes immunosuppression in the pancreatic tumor microenvironment
por: Choueiry, Fouad, et al.
Publicado: (2020)

Reducing the immunosuppressive tumor microenvironment enhances photoimmunotherapy efficacy
por: Sioud, Mouldy
Publicado: (2021)

Advances in Hypofractionated Irradiation-Induced Immunosuppression of Tumor Microenvironment
por: Wang, Yuxia
Publicado: (2021)

BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment
por: Liu, Wei, et al.
Publicado: (2022)

Immunosuppressive Microenvironment in Neuroblastoma
por: Pistoia, Vito, et al.
Publicado: (2013)

The Tumor Microenvironment: A Pitch for Multiple Players
por: Schiavoni, Giovanna, et al.
Publicado: (2013)

Interleukin-35 as an Emerging Player in Tumor Microenvironment
por: Xue, Wenhua, et al.
Publicado: (2019)

Crucial role of inflammatory monocytes in antitumor immunity
por: Pommier, Arnaud, et al.
Publicado: (2013)

Could the tumor-associated microbiota be the new multi-faceted player in the tumor microenvironment?
por: Goubet, Anne-Gaëlle
Publicado: (2023)

Hypoxia-Driven Immunosuppressive Metabolites in the Tumor Microenvironment: New Approaches for Combinational Immunotherapy
por: Li, Yiliang, et al.
Publicado: (2018)

The Tumor Microenvironment in Neuroblastoma: New Players, New Mechanisms of Interaction and New Perspectives
por: Blavier, Laurence, et al.
Publicado: (2020)

Involvement of local renin‐angiotensin system in immunosuppression of tumor microenvironment
por: Nakamura, Kenta, et al.
Publicado: (2017)

Functional Regulation of Ginsenosides on Myeloid Immunosuppressive Cells in the Tumor Microenvironment
por: Zhang, Yanfei, et al.
Publicado: (2019)

GARP: A Key Target to Evaluate Tumor Immunosuppressive Microenvironment
por: Bouchard, Alexanne, et al.
Publicado: (2021)

Critical immunosuppressive effect of MDSC-derived exosomes in the tumor microenvironment
por: Rashid, Mohammad H., et al.
Publicado: (2021)

Pivotal factors associated with the immunosuppressive tumor microenvironment and melanoma metastasis
por: Zhang, Chuan, et al.
Publicado: (2021)

Overexpression of SMS in the tumor microenvironment is associated with immunosuppression in hepatocellular carcinoma
por: Xiang, Lin, et al.
Publicado: (2022)

Context-Specific Determinants of the Immunosuppressive Tumor Microenvironment in Pancreatic Cancer
por: Falcomatà, Chiara, et al.
Publicado: (2023)

An integrated overview of the immunosuppression features in the tumor microenvironment of pancreatic cancer
por: Guo, Jinglong, et al.
Publicado: (2023)

Mediating immunosuppressive functions: a new perspective on the complex immunological properties of SEMA4D in the tumor microenvironment
por: Zeng, Shujie, et al.
Publicado: (2023)

Multiple Myeloma Macrophages: Pivotal Players in the Tumor Microenvironment
por: Berardi, Simona, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_tee6ifv22u49taee5rl15t228t