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Structure-Based Virtual Screening Allows the Identification of Efficient Modulators of E-Cadherin-Mediated Cell–Cell Adhesion

Cadherins are a large family of transmembrane calcium-dependent cell adhesion proteins that orchestrate adherens junction formation and are crucially involved in tissue morphogenesis. Due to their important role in cancer development and metastasis, cadherins can be considered attractive targets for...

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Detalles Bibliográficos
Autores principales: Dalle Vedove, Andrea, Falchi, Federico, Donini, Stefano, Dobric, Aurelie, Germain, Sebastien, Di Martino, Giovanni Paolo, Prosdocimi, Tommaso, Vettraino, Chiara, Torretta, Archimede, Cavalli, Andrea, Rigot, Veronique, André, Frederic, Parisini, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678102/
https://www.ncbi.nlm.nih.gov/pubmed/31373305
http://dx.doi.org/10.3390/ijms20143404