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Anti-Apoptotic Effect of G-Protein-Coupled Receptor 40 Activation on Tumor Necrosis Factor-α-Induced Injury of Rat Proximal Tubular Cells

G-protein-coupled receptor 40 (GPR40) has an anti-apoptotic effect in pancreatic β-cells. However, its role in renal tubular cell apoptosis remains unclear. To explore the role of GPR40 in renal tubular apoptosis, a two-week unilateral ureteral obstruction (UUO) mouse model was used. The protein exp...

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Detalles Bibliográficos
Autores principales: Kim, Chang Seong, Joo, Soo Yeon, Kim, In Jin, Choi, Hoon-In, Bae, Eun Hui, Kim, Soo Wan, Ma, Seong Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678114/
https://www.ncbi.nlm.nih.gov/pubmed/31295865
http://dx.doi.org/10.3390/ijms20143386