Hypoxia Modulates Effects of Fatty Acids on NES2Y Human Pancreatic β-cells

Saturated fatty acids (FAs) induce apoptosis in the human pancreatic NES2Y β-cell line while unsaturated FAs have nearly no detrimental effect. Moreover, unsaturated FAs are capable of inhibiting the pro-apoptotic effect of saturated FAs. Hypoxia is also known to have deleterious effects on β-cells...

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Detalles Bibliográficos
Autores principales: Šrámek, Jan, Němcová-Fürstová, Vlasta, Polák, Jan, Kovář, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678120/
https://www.ncbi.nlm.nih.gov/pubmed/31336948
http://dx.doi.org/10.3390/ijms20143441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678120/
https://www.ncbi.nlm.nih.gov/pubmed/31336948
http://dx.doi.org/10.3390/ijms20143441

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