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Recurrent DMD Deletions Highlight Specific Role of Dp71 Isoform in Soft-Tissue Sarcomas

Soft-tissue sarcomas (STS) are rare tumors whose oncogenesis remains unknown and for which no common therapeutic target has yet been identified. Analysis of 318 STS by CGH array evidenced a frequent deletion affecting the DMD gene (encoding dystrophin isoforms) in 16.5% of STS, including sarcomas wi...

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Detalles Bibliográficos
Autores principales: Mauduit, Olivier, Delcroix, Vanessa, Lesluyes, Tom, Pérot, Gaëlle, Lagarde, Pauline, Lartigue, Lydia, Blay, Jean-Yves, Chibon, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678178/
https://www.ncbi.nlm.nih.gov/pubmed/31266185
http://dx.doi.org/10.3390/cancers11070922