DNA-Repair Gene Mutations Are Highly Prevalent in Circulating Tumour DNA from Multiple Myeloma Patients

Mutational characterisation utilising plasma (PL)-derived circulating tumour DNA (ctDNA) in multiple myeloma (MM) has been recently described. Mutational analyses of paired bone marrow (BM) MM cell DNA and ctDNA from 76 patients (n = 24, new diagnosis (ND), n = 52, relapsed/refractory (RR)) for (ras...

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Detalles Bibliográficos
Autores principales: Mithraprabhu, Sridurga, Hocking, Jay, Ramachandran, Malarmathy, Choi, Kawa, Klarica, Daniela, Khong, Tiffany, Reynolds, John, Spencer, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678219/
https://www.ncbi.nlm.nih.gov/pubmed/31261969
http://dx.doi.org/10.3390/cancers11070917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678219/
https://www.ncbi.nlm.nih.gov/pubmed/31261969
http://dx.doi.org/10.3390/cancers11070917

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