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Molecular Mechanisms of p63-Mediated Squamous Cancer Pathogenesis

The p63 gene is a member of the p53/p63/p73 family of transcription factors and plays a critical role in development and homeostasis of squamous epithelium. p63 is transcribed as multiple isoforms; ΔNp63α, the predominant p63 isoform in stratified squamous epithelium, is localized to the basal cells...

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Detalles Bibliográficos
Autores principales: Moses, Michael A., George, Andrea L., Sakakibara, Nozomi, Mahmood, Kanwal, Ponnamperuma, Roshini M., King, Kathryn E., Weinberg, Wendy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678256/
https://www.ncbi.nlm.nih.gov/pubmed/31340447
http://dx.doi.org/10.3390/ijms20143590