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Identification of Withaferin A as a Potential Candidate for Anti-Cancer Therapy in Non-Small Cell Lung Cancer

Low response rate and recurrence are common issues in lung cancer; thus, identifying a potential compound for these patients is essential. Utilizing an in silico screening method, we identified withaferin A (WA), a cell-permeable steroidal lactone initially extracted from Withania somnifera, as a po...

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Detalles Bibliográficos
Autores principales: Hsu, Jade H.-M., Chang, Peter M.-H., Cheng, Tai-Shan, Kuo, Yu-Lun, Wu, Alexander T.-H., Tran, Thu-Ha, Yang, Yun-Hsuan, Chen, Jing-Ming, Tsai, Yu-Chen, Chu, Yeh-Shiu, Huang, Tse- Hung, Huang, Chi-Ying F., Lai, Jin-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678286/
https://www.ncbi.nlm.nih.gov/pubmed/31319622
http://dx.doi.org/10.3390/cancers11071003