Heightened JNK Activation and Reduced XIAP Levels Promote TRAIL and Sunitinib-Mediated Apoptosis in Colon Cancer Models

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potent inducer of apoptosis that may be a promising agent in cancer therapy due to its selectivity toward tumor cells. However, many cancer cells are resistant to TRAIL due to defects in apoptosis signaling or activation of surviva...

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Detalles Bibliográficos
Autores principales: Mahalingam, Devalingam, Carew, Jennifer S., Espitia, Claudia M., Cool, Robbert H., Giles, Francis J., de Jong, Steven, Nawrocki, Steffan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678293/
https://www.ncbi.nlm.nih.gov/pubmed/31248045
http://dx.doi.org/10.3390/cancers11070895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678293/
https://www.ncbi.nlm.nih.gov/pubmed/31248045
http://dx.doi.org/10.3390/cancers11070895

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