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The Unsolved Puzzle of c-Rel in B Cell Lymphoma

Aberrant constitutive activation of Rel/NF-κB transcription factors is a hallmark of numerous cancers. Of the five Rel family members, c-Rel has the strongest direct links to tumorigenesis. c-Rel is the only member that can malignantly transform lymphoid cells in vitro. Furthermore, c-Rel is implica...

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Detalles Bibliográficos
Autores principales: Kober-Hasslacher, Maike, Schmidt-Supprian, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678315/
https://www.ncbi.nlm.nih.gov/pubmed/31277480
http://dx.doi.org/10.3390/cancers11070941