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HIF-1α is Overexpressed in Odontogenic Keratocyst Suggesting Activation of HIF-1α and NOTCH1 Signaling Pathways

Background: The odontogenic keratocyst (OKC) is an odontogenic cyst that shows aggressive and intriguing biological behavior. It is suggested that a hypoxic environment occurs in OKC, which led us to investigate the immunoexpression and location of hypoxia-inducible factor 1-alpha (HIF-1α) and other...

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Detalles Bibliográficos
Autores principales: Miranda da Costa, Natacha Malu, Saab Abe, Caio Tadashi, Mitre, Geovanni Pereira, Mesquita, Ricardo Alves, da Silva Kataoka, Maria Sueli, Ribeiro Ribeiro, André Luis, Jaeger, Ruy Gastaldoni, Alves-Júnior, Sérgio de Melo, Smith, Andrew Mark, Pinheiro, João de Jesus Viana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678339/
https://www.ncbi.nlm.nih.gov/pubmed/31319505
http://dx.doi.org/10.3390/cells8070731