Cell Type-Specific TGF-β Mediated EMT in 3D and 2D Models and Its Reversal by TGF-β Receptor Kinase Inhibitor in Ovarian Cancer Cell Lines

Transcriptome profiling of 3D models compared to 2D models in various cancer cell lines shows differential expression of TGF-β-mediated and cell adhesion pathways. Presence of TGF-β in these cell lines shows an increased invasion potential which is specific to cell type. In the present study, we ide...

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Detalles Bibliográficos
Autores principales: Al Ameri, Wafa, Ahmed, Ikhlak, Al-Dasim, Fatima M., Ali Mohamoud, Yasmin, Al-Azwani, Iman K., Malek, Joel A., Karedath, Thasni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678358/
https://www.ncbi.nlm.nih.gov/pubmed/31336560
http://dx.doi.org/10.3390/ijms20143568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678358/
https://www.ncbi.nlm.nih.gov/pubmed/31336560
http://dx.doi.org/10.3390/ijms20143568

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