Morin Hydrate Reverses Cisplatin Resistance by Impairing PARP1/HMGB1-Dependent Autophagy in Hepatocellular Carcinoma

Chemoresistance is a major obstacle that limits the benefits of cisplatin-based chemotherapy in various cancers, including hepatocellular carcinoma. De-regulation of the poly(ADP-ribose) polymerase 1 (PARP1)/high-mobility group box 1 (HMGB1) signaling pathway has been proposed as an important mechan...

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Detalles Bibliográficos
Autores principales: Singh, Mahendra Pal, Cho, Hee Jun, Kim, Jong-Tae, Baek, Kyoung Eun, Lee, Hee Gu, Kang, Sun Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678360/
https://www.ncbi.nlm.nih.gov/pubmed/31311167
http://dx.doi.org/10.3390/cancers11070986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678360/
https://www.ncbi.nlm.nih.gov/pubmed/31311167
http://dx.doi.org/10.3390/cancers11070986

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