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Reduced Expression of Sprouty1 Contributes to the Aberrant Proliferation and Impaired Apoptosis of Acute Myeloid Leukemia Cells

In most of the acute myeloid leukemia patients there is an aberrant tyrosine kinase activity. The prototype of Sprouty proteins was originally identified in Drosophila melanogaster as antagonists of Breathless, the mammalian ortholog of fibroblast growth factor receptor. Usually, SPRY family members...

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Detalles Bibliográficos
Autores principales: Rosso, Valentina, Panuzzo, Cristina, Petiti, Jessica, Carturan, Sonia, Dragani, Matteo, Andreani, Giacomo, Fava, Carmen, Saglio, Giuseppe, Bracco, Enrico, Cilloni, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678378/
https://www.ncbi.nlm.nih.gov/pubmed/31277439
http://dx.doi.org/10.3390/jcm8070972