High Mobility Group Box 1 Mediates TMAO-Induced Endothelial Dysfunction

The intestinal microbe-derived metabolite trimethylamine N-oxide (TMAO) is implicated in the pathogenesis of cardiovascular diseases (CVDs). The molecular mechanisms of how TMAO induces atherosclerosis and CVDs’ progression are still unclear. In this regard, high-mobility group box protein 1 (HMGB1)...

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Detalles Bibliográficos
Autores principales: Singh, Gurinder Bir, Zhang, Yang, Boini, Krishna M., Koka, Saisudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678463/
https://www.ncbi.nlm.nih.gov/pubmed/31336567
http://dx.doi.org/10.3390/ijms20143570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678463/
https://www.ncbi.nlm.nih.gov/pubmed/31336567
http://dx.doi.org/10.3390/ijms20143570

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