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High Mobility Group Box 1 Mediates TMAO-Induced Endothelial Dysfunction
The intestinal microbe-derived metabolite trimethylamine N-oxide (TMAO) is implicated in the pathogenesis of cardiovascular diseases (CVDs). The molecular mechanisms of how TMAO induces atherosclerosis and CVDs’ progression are still unclear. In this regard, high-mobility group box protein 1 (HMGB1)...
Autores principales: | Singh, Gurinder Bir, Zhang, Yang, Boini, Krishna M., Koka, Saisudha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678463/ https://www.ncbi.nlm.nih.gov/pubmed/31336567 http://dx.doi.org/10.3390/ijms20143570 |
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