Ischemia Is Related to Tumour Genetics in Uveal Melanoma

Hypoxia-inducible factor 1-alpha (HIF1a) and its regulator von Hippel–Lindau protein (VHL) play an important role in tumour ischemia. Currently, drugs that target HIF1a are being developed to treat malignancies. Although HIF1a is known to be expressed in uveal melanoma (UM), it is as yet unknown whi...

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Detalles Bibliográficos
Autores principales: Brouwer, Niels J., Wierenga, Annemijn P. A., Gezgin, Gülçin, Marinkovic, Marina, Luyten, Gregorius P. M., Kroes, Wilma G. M., Versluis, Mieke, van der Velden, Pieter A., Verdijk, Robert M., Jager, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678476/
https://www.ncbi.nlm.nih.gov/pubmed/31323773
http://dx.doi.org/10.3390/cancers11071004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678476/
https://www.ncbi.nlm.nih.gov/pubmed/31323773
http://dx.doi.org/10.3390/cancers11071004

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