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Arachidonic Acid Evokes an Increase in Intracellular Ca(2+) Concentration and Nitric Oxide Production in Endothelial Cells from Human Brain Microcirculation
It has long been known that the conditionally essential polyunsaturated arachidonic acid (AA) regulates cerebral blood flow (CBF) through its metabolites prostaglandin E2 and epoxyeicosatrienoic acid, which act on vascular smooth muscle cells and pericytes to vasorelax cerebral microvessels. However...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678502/ https://www.ncbi.nlm.nih.gov/pubmed/31323976 http://dx.doi.org/10.3390/cells8070689 |