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Arachidonic Acid Evokes an Increase in Intracellular Ca(2+) Concentration and Nitric Oxide Production in Endothelial Cells from Human Brain Microcirculation

It has long been known that the conditionally essential polyunsaturated arachidonic acid (AA) regulates cerebral blood flow (CBF) through its metabolites prostaglandin E2 and epoxyeicosatrienoic acid, which act on vascular smooth muscle cells and pericytes to vasorelax cerebral microvessels. However...

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Detalles Bibliográficos
Autores principales: Berra-Romani, Roberto, Faris, Pawan, Negri, Sharon, Botta, Laura, Genova, Tullio, Moccia, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678502/
https://www.ncbi.nlm.nih.gov/pubmed/31323976
http://dx.doi.org/10.3390/cells8070689