Glucagon-Like Peptide-1 Receptor Agonist Attenuates Autophagy to Ameliorate Pulmonary Arterial Hypertension through Drp1/NOX- and Atg-5/Atg-7/Beclin-1/LC3β Pathways

Mitochondrial dysfunction is associated with cardiovascular diseases and diabetes. Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling, and the abnormal proliferation, apoptosis and migration of pulmonary arterial smooth muscle cells (PASMCs). The glucagon-like pe...

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Detalles Bibliográficos
Autores principales: Wu, Yi-Chia, Wang, Wei-Ting, Lee, Su-Shin, Kuo, Yur-Ren, Wang, Ya-Chin, Yen, Shih-Jung, Lee, Mei-Yueh, Yeh, Jwu-Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678531/
https://www.ncbi.nlm.nih.gov/pubmed/31336911
http://dx.doi.org/10.3390/ijms20143435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678531/
https://www.ncbi.nlm.nih.gov/pubmed/31336911
http://dx.doi.org/10.3390/ijms20143435

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