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Glucagon-Like Peptide-1 Receptor Agonist Attenuates Autophagy to Ameliorate Pulmonary Arterial Hypertension through Drp1/NOX- and Atg-5/Atg-7/Beclin-1/LC3β Pathways
Mitochondrial dysfunction is associated with cardiovascular diseases and diabetes. Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling, and the abnormal proliferation, apoptosis and migration of pulmonary arterial smooth muscle cells (PASMCs). The glucagon-like pe...
Autores principales: | Wu, Yi-Chia, Wang, Wei-Ting, Lee, Su-Shin, Kuo, Yur-Ren, Wang, Ya-Chin, Yen, Shih-Jung, Lee, Mei-Yueh, Yeh, Jwu-Lai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678531/ https://www.ncbi.nlm.nih.gov/pubmed/31336911 http://dx.doi.org/10.3390/ijms20143435 |
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