Proteomic Analysis of Breast Cancer Resistance to the Anticancer Drug RH1 Reveals the Importance of Cancer Stem Cells

Antitumor drug resistance remains a major challenge in cancer chemotherapy. Here we investigated the mechanism of acquired resistance to a novel anticancer agent RH1 designed to be activated in cancer cells by the NQO1 enzyme. Data show that in some cancer cells RH1 may act in an NQO1-independent wa...

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Detalles Bibliográficos
Autores principales: Kuciauskas, Dalius, Dreize, Nadezda, Ger, Marija, Kaupinis, Algirdas, Zemaitis, Kristijonas, Stankevicius, Vaidotas, Suziedelis, Kestutis, Cicenas, Jonas, Graves, Lee M., Valius, Mindaugas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678540/
https://www.ncbi.nlm.nih.gov/pubmed/31336714
http://dx.doi.org/10.3390/cancers11070972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678540/
https://www.ncbi.nlm.nih.gov/pubmed/31336714
http://dx.doi.org/10.3390/cancers11070972

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