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Proteomic Analysis of Breast Cancer Resistance to the Anticancer Drug RH1 Reveals the Importance of Cancer Stem Cells

Antitumor drug resistance remains a major challenge in cancer chemotherapy. Here we investigated the mechanism of acquired resistance to a novel anticancer agent RH1 designed to be activated in cancer cells by the NQO1 enzyme. Data show that in some cancer cells RH1 may act in an NQO1-independent wa...

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Detalles Bibliográficos
Autores principales:	Kuciauskas, Dalius, Dreize, Nadezda, Ger, Marija, Kaupinis, Algirdas, Zemaitis, Kristijonas, Stankevicius, Vaidotas, Suziedelis, Kestutis, Cicenas, Jonas, Graves, Lee M., Valius, Mindaugas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678540/ https://www.ncbi.nlm.nih.gov/pubmed/31336714 http://dx.doi.org/10.3390/cancers11070972

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