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Exploiting Mitochondrial Vulnerabilities to Trigger Apoptosis Selectively in Cancer Cells
The transformation of normal cells to the cancerous stage involves multiple genetic changes or mutations leading to hyperproliferation, resistance to apoptosis, and evasion of the host immune system. However, to accomplish hyperproliferation, cancer cells undergo profound metabolic reprogramming inc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678564/ https://www.ncbi.nlm.nih.gov/pubmed/31261935 http://dx.doi.org/10.3390/cancers11070916 |