Cargando…

Exploiting Mitochondrial Vulnerabilities to Trigger Apoptosis Selectively in Cancer Cells

The transformation of normal cells to the cancerous stage involves multiple genetic changes or mutations leading to hyperproliferation, resistance to apoptosis, and evasion of the host immune system. However, to accomplish hyperproliferation, cancer cells undergo profound metabolic reprogramming inc...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, Christopher, Pandey, Siyaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678564/
https://www.ncbi.nlm.nih.gov/pubmed/31261935
http://dx.doi.org/10.3390/cancers11070916