Activating Mutations in PTPN11 and KRAS in Canine Histiocytic Sarcomas

While the genetic contributions to the predisposition of Bernese mountain dogs (BMDs) to histiocytic sarcoma (HS) remains unclear, some insights into key genetic drivers have been gained. Our group recently reported a mutation in the PTPN11 gene (E76K). We have now identified a second missense mutat...

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Detalles Bibliográficos
Autores principales: Takada, Marilia, Smyth, Lauren A., Thaiwong, Tuddow, Richter, Marlee, Corner, Sarah M., Schall, Peter Z., Kiupel, Matti, Yuzbasiyan-Gurkan, Vilma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678586/
https://www.ncbi.nlm.nih.gov/pubmed/31277422
http://dx.doi.org/10.3390/genes10070505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678586/
https://www.ncbi.nlm.nih.gov/pubmed/31277422
http://dx.doi.org/10.3390/genes10070505

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