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The Mode of Stem Cell Division Is Dependent on the Differential Interaction of β-Catenin with the Kat3 Coactivators CBP or p300

Normal long-term repopulating somatic stem cells (SSCs) preferentially divide asymmetrically, with one daughter cell remaining in the niche and the other going on to be a transient amplifying cell required for generating new tissue in homeostatic maintenance and repair processes, whereas cancer stem...

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Detalles Bibliográficos
Autores principales: Lukaszewicz, Agnes I., Nguyen, Cu, Melendez, Elizabeth, Lin, David P., Teo, Jia-Ling, Lai, Keane K. Y., Huttner, Wieland B., Shi, Song-Hai, Kahn, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678591/
https://www.ncbi.nlm.nih.gov/pubmed/31324005
http://dx.doi.org/10.3390/cancers11070962