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Gas6 Prevents Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells via Production of PGE(2), PGD(2) and Their Receptors

The epithelial-mesenchymal transition (EMT) is important in organ fibrosis. We hypothesized that growth arrest-specific protein 6 (Gas6) and its underlying mechanisms play roles in the prevention of EMT in alveolar epithelial cells (ECs). In this study, to determine whether Gas6 prevents TGF-β1-indu...

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Detalles Bibliográficos
Autores principales: Jung, Jihye, Lee, Ye-Ji, Choi, Youn-Hee, Park, Eun-Mi, Kim, Hee-Sun, Kang, Jihee L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678614/
https://www.ncbi.nlm.nih.gov/pubmed/31247991
http://dx.doi.org/10.3390/cells8070643