The d16HER2 Splice Variant: A Friend or Foe of HER2-Positive Cancers?

Human epidermal growth factor receptor 2 (ERBB2 or HER2) amplification/overexpression is associated with a particularly aggressive molecular subtype of breast cancer (BC), characterized by a poor prognosis, increased metastatic potential, and disease recurrence. As only approximately 50% of HER2-pos...

Descripción completa

Detalles Bibliográficos
Autores principales: Castagnoli, Lorenzo, Ladomery, Michael, Tagliabue, Elda, Pupa, Serenella M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678616/
https://www.ncbi.nlm.nih.gov/pubmed/31261614
http://dx.doi.org/10.3390/cancers11070902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678616/
https://www.ncbi.nlm.nih.gov/pubmed/31261614
http://dx.doi.org/10.3390/cancers11070902

Ejemplares similares