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The d16HER2 Splice Variant: A Friend or Foe of HER2-Positive Cancers?
Human epidermal growth factor receptor 2 (ERBB2 or HER2) amplification/overexpression is associated with a particularly aggressive molecular subtype of breast cancer (BC), characterized by a poor prognosis, increased metastatic potential, and disease recurrence. As only approximately 50% of HER2-pos...
Autores principales: | Castagnoli, Lorenzo, Ladomery, Michael, Tagliabue, Elda, Pupa, Serenella M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678616/ https://www.ncbi.nlm.nih.gov/pubmed/31261614 http://dx.doi.org/10.3390/cancers11070902 |
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