Impact of Q141K on the Transport of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors by ABCG2

The ATP-binding cassette transporter ABCG2 is expressed in various organs, such as the small intestine, liver, and kidney, and influences the pharmacokinetics of drugs that are its substrates. ABCG2 is also expressed by cancer cells and mediates resistance to anticancer agents by promoting the efflu...

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Detalles Bibliográficos
Autores principales: Inoue, Yutaka, Morita, Takashi, Onozuka, Mari, Saito, Ken-ichi, Sano, Kazumi, Hanada, Kazuhiko, Kondo, Masami, Nakamura, Yoichi, Kishino, Tohru, Nakagawa, Hiroshi, Ikegami, Yoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678652/
https://www.ncbi.nlm.nih.gov/pubmed/31340525
http://dx.doi.org/10.3390/cells8070763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678652/
https://www.ncbi.nlm.nih.gov/pubmed/31340525
http://dx.doi.org/10.3390/cells8070763

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