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Inhibition of Protein Phosphatase 1 Stimulates Noncanonical ER Stress eIF2α Activation to Enhance Fisetin-induced Chemosensitivity in HDAC Inhibitor-resistant Hepatocellular Carcinoma Cells

Hepatocellular carcinoma (HCC) is a common fatal type of malignant tumor that has highly metastatic and recurrent properties. Fisetin is a natural flavonoid found in various vegetables and fruits which exhibits anti-cancer and anti-inflammatory properties, as well as other effects. Thus, we hypothes...

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Detalles Bibliográficos
Autores principales: Liu, Yi-Sheng, Chang, Yu-Chun, Kuo, Wei-Wen, Chen, Ming-Cheng, Hsu, Hsi-Hsien, Tu, Chuan-Chou, Yeh, Yu-Lan, Viswanadha, Vijaya Padma, Liao, Po-Hsiang, Huang, Chih-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678694/
https://www.ncbi.nlm.nih.gov/pubmed/31261976
http://dx.doi.org/10.3390/cancers11070918