Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disorder. It is mainly caused by mutations in genes encoding sarcomere proteins. Mutant forms of these highly abundant proteins likely stress the protein quality control (PQC) system of cardiomyocytes. The PQC system, together wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Dorsch, Larissa M., Schuldt, Maike, dos Remedios, Cristobal G., Schinkel, Arend F. L., de Jong, Peter L., Michels, Michelle, Kuster, Diederik W. D., Brundel, Bianca J. J. M., van der Velden, Jolanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678711/
https://www.ncbi.nlm.nih.gov/pubmed/31323898
http://dx.doi.org/10.3390/cells8070741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678711/
https://www.ncbi.nlm.nih.gov/pubmed/31323898
http://dx.doi.org/10.3390/cells8070741

Ejemplares similares