Mutations in the ND2 Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells

Multiprotein complexes of the mitochondrial electron transport chain form associations to generate supercomplexes. The relationship between tumor cell ability to assemble mitochondrial supercomplexes, tumorigenesis and metastasis has not been studied thoroughly. The mitochondrial and metabolic diffe...

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Detalles Bibliográficos
Autores principales: Marco-Brualla, Joaquín, Al-Wasaby, Sameer, Soler, Ruth, Romanos, Eduardo, Conde, Blanca, Justo-Méndez, Raquel, Enríquez, José A., Fernández-Silva, Patricio, Martínez-Lostao, Luis, Villalba, Martín, Moreno-Loshuertos, Raquel, Anel, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678765/
https://www.ncbi.nlm.nih.gov/pubmed/31330915
http://dx.doi.org/10.3390/cancers11071027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678765/
https://www.ncbi.nlm.nih.gov/pubmed/31330915
http://dx.doi.org/10.3390/cancers11071027

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