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Mutations in the ND2 Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells
Multiprotein complexes of the mitochondrial electron transport chain form associations to generate supercomplexes. The relationship between tumor cell ability to assemble mitochondrial supercomplexes, tumorigenesis and metastasis has not been studied thoroughly. The mitochondrial and metabolic diffe...
Autores principales: | Marco-Brualla, Joaquín, Al-Wasaby, Sameer, Soler, Ruth, Romanos, Eduardo, Conde, Blanca, Justo-Méndez, Raquel, Enríquez, José A., Fernández-Silva, Patricio, Martínez-Lostao, Luis, Villalba, Martín, Moreno-Loshuertos, Raquel, Anel, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678765/ https://www.ncbi.nlm.nih.gov/pubmed/31330915 http://dx.doi.org/10.3390/cancers11071027 |
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